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1

A Medicinal Chemistry Perspective on 4-Aminoquinoline Antimalarial Drugs

Bray, Patrick, Park, B., Asadollaly, Egbaleh, Biagini, Giancarlo, Jeyadevan, J., Berry, Neil, Ward, Stephen, O' Neill, Paul

Journal:

Current Topics in Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 425 KB

english, 2006

2

Characteristics of the velocity profile at tidal-stream energy sites

Lewis, M., Neill, S.P., Robins, P., Hashemi, M.R., Ward, S.

Journal:

Renewable Energy

Year:

2017

Language:

english

File:

PDF, 7.12 MB

english, 2017

3

Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease

Tracey K Murray, Marcus J Messenger, Mark A Ward, Sandra Woodhouse, David J Osborne, Susan Duty, Michael J O'Neill

Journal:

Pharmacology Biochemistry and Behavior

Year:

2002

Language:

english

File:

PDF, 491 KB

english, 2002

4

Characterising the spatial and temporal variability of the tidal-stream energy resource over the northwest European shelf seas

Robins, Peter E., Neill, Simon P., Lewis, Matt J., Ward, Sophie L.

Journal:

Year:

2015

Language:

english

File:

PDF, 3.95 MB

english, 2015

5

VISUAL MASKING BY TRANSLATION EQUIVALENTS IN BILINGUALS

Journal:

Perceptual and Motor Skills

Year:

1977

Language:

english

File:

PDF, 228 KB

english, 1977

6

A translation-based generation effect in bilingual recall and recognition

Ward O’Neill, Lise Roy, Roger Tremblay

Journal:

Memory & Cognition

Year:

1993

Language:

english

File:

PDF, 1.08 MB

english, 1993

7

The neuronal nitric oxide synthase inhibitor, TRIM, as a neuroprotective agent: effects in models of cerebral ischaemia using histological and magnetic resonance imaging techniques

Kristin K Haga, Lloyd J Gregory, Caroline A Hicks, Mark A Ward, John S Beech, Phillip W Bath, Steven C.R Williams, Michael J O'Neill

Journal:

Year:

2003

Language:

english

File:

PDF, 1.17 MB

english, 2003

8

4-Aminoquinolines—Past, present, and future; A chemical perspective

Paul M. O'Neill, Patrick G. Bray, Shaun R. Hawley, Stephen A. Ward, B.Kevin Park

Journal:

Pharmacology & Therapeutics

Year:

1998

Language:

english

File:

PDF, 3.08 MB

english, 1998

9

Reproductive performance of pubertal red deer (Cervus elaphus) hinds: Effects of genetic introgression of wapiti subspecies on pregnancy rates at 18 months of age

G.W. Asher, J.A. Archer, I.C. Scott, K.T. O’Neill, J. Ward, R.P. Littlejohn

Journal:

Animal Reproduction Science

Year:

2005

Language:

english

File:

PDF, 243 KB

english, 2005

10

Current drug development portfolio for antimalarial therapies

Giancarlo A Biagini, Paul M O’Neill, Patrick G Bray, Stephen A Ward

Journal:

Current Opinion in Pharmacology

Year:

2005

Language:

english

File:

PDF, 144 KB

english, 2005

11

Microemulsions as Topical Drug Delivery Vehicles. I. Characterization of a Model System

Osborne, David U., Ward, Anthony J.I., O'neill, Kilian J.

Journal:

Drug Development and Industrial Pharmacy

Year:

1988

Language:

english

File:

PDF, 547 KB

english, 1988

12

Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era

Nixon, Gemma L, Pidathala, Chandrakala, Shone, Alison E, Antoine, Thomas, Fisher, Nicholas, O’Neill, Paul M, Ward, Stephen A, Biagini, Giancarlo A

Journal:

Future Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 5.30 MB

english, 2013

13

Microemulsions as topical drug delivery vehicles: in-vitro transdermal studies of a model hydrophilic drug

D. W. Osborne, A. J. I. Ward, K. J. O'neill

Journal:

Journal of Pharmacy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 443 KB

english, 1991

14

WORD-IMAGERY EFFECTS ON RECOLLECTION AND FAMILIARITY IN RECOGNITION MEMORY

Journal:

Perceptual and Motor Skills

Year:

2005

Language:

english

File:

PDF, 381 KB

english, 2005

15

Tidal stream resource assessment uncertainty due to flow asymmetry and turbine yaw misalignment

Piano, M., Neill, S.P., Lewis, M.J., Robins, P.E., Hashemi, M.R., Davies, A.G., Ward, S.L., Roberts, M.J.

Journal:

Renewable Energy

Year:

2017

Language:

english

File:

PDF, 4.83 MB

english, 2017

16

Bilingual Recognition of Concrete and Abstract Sentences

O'Neill, Ward, Dion, Andre

Journal:

Perceptual and Motor Skills

Year:

1983

Language:

english

File:

PDF, 275 KB

english, 1983

17

Stimulus and Response Set in Information Processing

O'Neill, Ward, Gascon, Hubert

Journal:

Perceptual and Motor Skills

Year:

1978

Language:

english

File:

PDF, 148 KB

english, 1978

18

Tidal stream resource characterisation in progressive versus standing wave systems

Ward, Sophie L., Robins, Peter E., Lewis, Matt J., Iglesias, Gregorio, Hashemi, M. Reza, Neill, Simon P.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.12 MB

english, 2018

19

Tidal range energy resource and optimization – Past perspectives and future challenges

Neill, Simon P., Angeloudis, Athanasios, Robins, Peter E., Walkington, Ian, Ward, Sophie L., Masters, Ian, Lewis, Matt J., Piano, Marco, Avdis, Alexandros, Piggott, Matthew D., Aggidis, George, Evans,

Journal:

Renewable Energy

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

20

Simultaneous Visual Discrimination in Rats: Training Strategies

Biederman, Gerald B., O'Neill, Ward

Journal:

Perceptual and Motor Skills

Year:

1969

Language:

english

File:

PDF, 179 KB

english, 1969

21

Ikaros increases normal apoptosis in adult erythroid cells

Dianne Pulte, Rocio A. Lopez, Shane T. Baker, Maureen Ward, Ellen Ritchie, Christine A. Richardson, David W. O'Neill, Arthur Bank

Journal:

American Journal of Hematology

Year:

2006

Language:

english

File:

PDF, 165 KB

english, 2006

22

Design and Synthesis of Endoperoxide Antimalarial Prodrug Models

Paul M. O'Neill, Paul A. Stocks, Matthew D. Pugh, Nuna C. Araujo, Edward E. Korshin, Jamie F. Bickley, Stephen A. Ward, Patrick G. Bray, Erica Pasini, Jill Davies, Edite Verissimo, Mario D. Bachi

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

23

Design and Synthesis of Endoperoxide Antimalarial Prodrug Models

Paul M. O'Neill, Paul A. Stocks, Matthew D. Pugh, Nuna C. Araujo, Edward E. Korshin, Jamie F. Bickley, Stephen A. Ward, Patrick G. Bray, Erica Pasini, Jill Davies, Edite Verissimo, Mario D. Bachi

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

24

Enantiomeric 1,2,4-Trioxanes Display Equivalent in vitro Antimalarial Activity Versus Plasmodium falciparum Malaria Parasites: Implications for the Molecular Mechanism of Action of the Artemisinins

Paul M. O’Neill, Sarah L. Rawe, Kristina Borstnik, Alison Miller, Stephen A. Ward, Patrick G. Bray, Jill Davies, Chang Ho Oh, Gary H. Posner

Journal:

Year:

2005

Language:

english

File:

PDF, 134 KB

english, 2005

25

ChemInform Abstract: Synthesis, Antimalarial Activity, and Molecular Modeling of Tebuquine Analogues.

P. M. O'NEILL, D. J. WILLOCK, S. R. HAWLEY, P. G. BRAY, R. C. STORR, S. A. WARD, B. K. PARK

Journal:

Year:

1997

File:

PDF, 31 KB

1997

26

ChemInform Abstract: A Carbonyl Oxide Route to Antimalarial Yingzhaosu A Analogues: Synthesis and Antimalarial Activity.

P. M. O'NEILL, N. L. SEARLE, K. J. RAYNES, J. L. MAGGS, S. A. WARD, R. C. STORR, B. K. PARK, G. H. POSNER

Journal:

Year:

1998

File:

PDF, 29 KB

1998

27

ChemInform Abstract: Application of the TMSOTf—AgClO4 Activator System to the Synthesis of Novel, Potent, C-10 Phenoxy Derivatives of Dihydroartemisinin.

Paul M. O'Neill, Alison Miller, Stephen A. Ward, B. Kevin Park, Feodor Scheinmann, Andrew V. Stachulski

Journal:

Year:

2000

File:

PDF, 31 KB

2000

28

ChemInform Abstract: Biomimetic Fe(II)-Mediated Degradation of Arteflene (Ro-42-1611). The First EPR Spin-Trapping Evidence for the Previously Postulated Secondary Carbon-Centered Cyclohexyl Radical.

Paul M. O'Neill, Laurence P. D. Bishop, Natalie L. Searle, James L. Maggs, Richard C. Storr, Stephen A. Ward, B. Kevin Park, Frank Mabbs

Journal:

Year:

2000

File:

PDF, 27 KB

2000

29

ChemInform Abstract: Regioselective Mukaiyama Hydroperoxysilylation of 2-Alkyl- or 2-Aryl-prop-2-en-1-ols: Application to a New Synthesis of 1,2,4-Trioxanes.

Paul M. O'Neill, Matthew Pugh, Jill Davies, Stephen A. Ward, B. Kevin Park

Journal:

Year:

2001

File:

PDF, 30 KB

2001

30

Co(thd)2: A Superior Catalyst for Aerobic Epoxidation and Hydroperoxysilylation of Unactivated Alkenes: Application to the Synthesis of Spiro-1,2,4-trioxanes.

Paul M. O'Neill, Stephen Hindley, Matthew D. Pugh, Jill Davies, Patrick G. Bray, B. Kevin Park, Dauda S. Kapu, Stephen A. Ward, Paul A. Stocks

Journal:

Year:

2004

File:

PDF, 117 KB

2004

31

Synthesis and Antimalarial Activities of a Diverse Set of Triazole-Containing Furamidine Analogues

Dr. Olivier Berger, Dr. Archana Kaniti, Christophe Tran van Ba, Prof. Henri Vial, Prof. Stephen A. Ward, Giancarlo A. Biagini, Dr. Patrick G. Bray, Prof. Paul M. O'Neill

Journal:

Year:

2011

Language:

english

File:

PDF, 578 KB

english, 2011

32

Comparative preclinical drug metabolism and pharmacokinetic evaluation of novel 4-aminoquinoline anti-malarials

Charles B. Davis, Ramesh Bambal, Ganesh S. Moorthy, Erin Hugger, Hong Xiang, Brian Kevin Park, Allison E. Shone, Paul M. O'Neill, Stephen A. Ward

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 202 KB

english, 2009

33

An infra-red study of conformational changes occurring during the drawing of PEMT, PET and PEMT/PET copolymer

P. Spiby, M.A. O'Neill, R.A. Duckett, I.M. Ward

Journal:

Year:

1992

Language:

english

File:

PDF, 530 KB

english, 1992

34

The effect of fluorine substitution on the haemotoxicity of Primaquine

Paul M. O'Neill, Malcolm D. Tingle, Roziahanim Mahmud, Richard C. Storr, Stephen A. Ward, B. Kevin Park

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 306 KB

english, 1995

35

Design, synthesis and antimalarial/anticancer evaluation of spermidine linked artemisinin conjugates designed to exploit polyamine transporters in Plasmodium falciparum and HL-60 cancer cell lines

James Chadwick, Michael Jones, Amy E. Mercer, Paul A. Stocks, Stephen A. Ward, B. Kevin Park, Paul M. O’Neill

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 626 KB

english, 2010

36

Diels–Alder/thiol–olefin co-oxygenation approach to antimalarials incorporating the 2,3-dioxabicyclo[3.3.1]nonane pharmacophore

Paul M. O’Neill, Edite Verissimo, Stephen A. Ward, Jill Davies, Edward E. Korshin, Nuna Araujo, Matthew D. Pugh, M. Lurdes S. Cristiano, Paul A. Stocks, Mario D. Bachi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

37

An efficient route into synthetically challenging bridged achiral 1,2,4,5-tetraoxanes with antimalarial activity

Gemma L. Ellis, Richard Amewu, Charlotte Hall, Karen Rimmer, Steven A. Ward, Paul M. O’Neill

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

38

Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors

Edite Verissimo, Neil Berry, Peter Gibbons, M. Lurdes S. Cristiano, Philip J. Rosenthal, Jiri Gut, Stephen A. Ward, Paul M. O’Neill

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 285 KB

english, 2008

39

Piperidine dispiro-1,2,4-trioxane analogues

Sunil Sabbani, Paul A. Stocks, Gemma L. Ellis, Jill Davies, Erik Hedenstrom, Stephen A. Ward, Paul M. O’Neill

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 227 KB

english, 2008

40

Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates

Nuna C.P. Araújo, Victoria Barton, Michael Jones, Paul A. Stocks, Stephen A. Ward, Jill Davies, Patrick G. Bray, Alison E. Shone, Maria L.S. Cristiano, Paul M. O’Neill

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 353 KB

english, 2009

41

Inhibiting Plasmodium cytochrome bc1: a complex issue

Victoria Barton, Nicholas Fisher, Giancarlo A Biagini, Stephen A Ward, Paul M O’Neill

Journal:

Current Opinion in Chemical Biology

Year:

2010

Language:

english

File:

PDF, 485 KB

english, 2010

42

Neutron reflectometry studies of exchange springs in DyFe2/YFe2 superlattices

J.D. O’Neill, S. Langridge, R.M. Dalgliesh, A.A. Zhukov, J.-M.L. Beaujour, G.J. Bowden, P.A.J. de Groot, B.D. Rainford, R.C.C. Ward, M.R. Wells

Journal:

Journal of Magnetism and Magnetic Materials

Year:

2004

Language:

english

File:

PDF, 185 KB

english, 2004

43

Field-dependent easy magnetic axes in epitaxially grown (1 1 0) DyFe2 film

G.J. Bowden, A.A. Zhukov, J-M.L. Beaujour, J.D. O’Neill, B.D. Rainford, P.A.J. de Groot, R.C.C. Ward, M.R. Wells, H. Küpfer

Journal:

Journal of Magnetism and Magnetic Materials

Year:

2004

Language:

english

File:

PDF, 179 KB

english, 2004

44

Co(thd)2: a superior catalyst for aerobic epoxidation and hydroperoxysilylation of unactivated alkenes: application to the synthesis of spiro-1,2,4-trioxanes

Paul M. O'Neill, Stephen Hindley, Matthew D. Pugh, Jill Davies, Patrick G. Bray, B.Kevin Park, Dauda S. Kapu, Stephen A. Ward, Paul A. Stocks

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 641 KB

english, 2003

45

Lewis acid catalysed rearrangements of unsaturated bicyclic [2.2.n] endoperoxides in the presence of vinyl silanes; access to novel Fenozan BO-7 analogues

Paul M. O’Neill, Sarah L. Rawe, Richard C. Storr, Stephen A. Ward, Gary H. Posner

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 173 KB

english, 2005

46

Regioselective Mukaiyama hydroperoxysilylation of 2-alkyl- or 2-aryl-prop-2-en-1-ols: application to a new synthesis of 1,2,4-trioxanes

Paul M O'Neill, Matthew Pugh, Jill Davies, Stephen A Ward, B.Kevin Park

Journal:

Tetrahedron Letters

Year:

2001

Language:

english

File:

PDF, 85 KB

english, 2001

47

The biomimetic iron-mediated degradation of arteflene (Ro-42-1611),an endoperoxide antimalarial: Implications for the mechanism of antimalarial activity

Paul M. O'Neill, Laurence P. Bishop, Natalie L. Searle, James L. Maggs, Stephen A. Ward, Patrick G. Bray, Richard C. Storr, B. Kevin Park

Journal:

Tetrahedron Letters

Year:

1997

Language:

english

File:

PDF, 252 KB

english, 1997

48

Application of the TMSOTfAgClO4 activator system to the synthesis of novel, potent, C-10 phenoxy derivatives of dihydroartemisinin

Paul M. O'Neill, Alison Miller, Stephen A. Ward, B.Kevin Park, Feodor Scheinmann, Andrew V. Stachulski

Journal:

Tetrahedron Letters

Year:

1999

Language:

english

File:

PDF, 252 KB

english, 1999

49

Movable radiation shields for the CLEO II silicon vertex detector

D.J. Dumas, C.W. Ward, J. Alexander, J. Cherwinka, D. Cinabro, J. Fast, S. Henderson, R. Morrison, M. O'Neill

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Year:

1998

Language:

english

File:

PDF, 685 KB

english, 1998

50

Exomphalos – a major or minor problem?

T. O'Neill, F. Kirby, K. O'Brien, D. Warde

Journal:

Pediatric Anesthesia

Year:

2002

Language:

english

File:

PDF, 253 KB

english, 2002

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